6 board-style questions on osteoarthritis in the PulseMD family medicine question bank — physician-reviewed, written against current guidelines with the reference cited on each question. Two free samples below; the full set with answers, explanations, and spaced review is free to start.
A 67-year-old woman presents with bilateral knee pain that has gradually worsened over the past 3 years. Pain is worse at the end of the day and with prolonged standing or walking. She reports morning stiffness lasting approximately 10-15 minutes each day. Physical examination reveals bony enlargement of both knees, crepitus with range of motion, and a small cool effusion on the right. There is no erythema or warmth. What is the most likely diagnosis?
A 68-year-old man with bilateral knee osteoarthritis has been managing his symptoms with acetaminophen 1000 mg three times daily and regular walking, but his pain has progressively worsened and now limits his daily activities. He has a history of stage 3 CKD (eGFR 38 mL/min) and a prior GI bleed from an NSAID-related gastric ulcer 2 years ago. His BMI is 28 kg/m2. What is the most appropriate next step in pharmacologic management?
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