10 board-style questions on lupus (sle) in the PulseMD family medicine question bank, written against current guidelines with the reference cited on each question. Two free samples below; the full set with answers, explanations, and spaced review is free to start.
A 45-year-old woman with a history of systemic lupus erythematosus presents with worsening dyspnea over 3 months. Her ECG shows right axis deviation (+120 degrees), tall R waves in V1, right atrial enlargement (peaked P waves in lead II > 2.5 mm), and T-wave inversions in the right precordial leads (V1-V4). Her prior ECG from 1 year ago showed a normal axis and no right-sided abnormalities. Which of the following is the most likely cause of these ECG findings?
A 35-year-old woman with a 10-year history of systemic lupus erythematosus (SLE) presents with exertional chest pain. She has no traditional cardiovascular risk factors except a mildly elevated LDL of 138 mg/dL. Her 10-year ASCVD risk score calculates to 1.8%. A coronary CT angiography reveals a non-obstructive 40% stenosis in the proximal LAD with mixed plaque. Which of the following best explains her premature atherosclerotic disease?
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