Anticoagulation: ABFM practice questions

20 board-style questions on anticoagulation in the PulseMD family medicine question bank — physician-reviewed, written against current guidelines with the reference cited on each question. Two free samples below; the full set with answers, explanations, and spaced review is free to start.

Sample question 1

A 48-year-old man was diagnosed with an unprovoked proximal deep vein thrombosis of the left popliteal and femoral veins 6 months ago. He has been on rivaroxaban 20 mg daily since diagnosis with no bleeding complications. Repeat compression ultrasonography shows complete resolution of the thrombus. He has no identifiable provoking risk factors (no surgery, immobilization, trauma, or malignancy). Thrombophilia workup is negative. He asks how long he should continue anticoagulation. What is the most appropriate recommendation?

  1. Discontinue anticoagulation now; 6 months is adequate for a first unprovoked DVT
  2. Continue rivaroxaban for a total of 12 months, then discontinue
  3. Consider extended (indefinite) anticoagulation with periodic reassessment of the risk-benefit balance
  4. Switch to aspirin 81 mg daily as a substitute for anticoagulation

Sample question 2

A 60-year-old man with no known bleeding risk presents with confirmed acute submassive pulmonary embolism. CT pulmonary angiography shows bilateral segmental PE with right ventricular dilation (RV/LV ratio 1.3). His blood pressure is 118/74 mmHg, heart rate is 112 bpm, and troponin is elevated at 0.15 ng/mL. He is hemodynamically stable. What is the most appropriate initial treatment?

  1. Inferior vena cava filter placement
  2. Therapeutic anticoagulation (LMWH or UFH) with close monitoring
  3. Referral for open surgical embolectomy
  4. Systemic thrombolysis with alteplase

Create a free PulseMD account to answer these, see the explanations, and practice five minutes a day.

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